Using the Horizon Oncospan cfDNA standard and the Twist Bioscience pan-cancer enrichment panel, we showcase the utility of SRSLY NGS library preparation in ctDNA variant calling.
This application note describes the utility of SRSLY in performing targeted sequence analysis of SAR-CoV-2 RNA-Seq libraries were generated with SRSLY within 3 hours. Subsequent enrichment of viral sequences can be performed with a user-preferred hybridization-based panel.
Cell-free DNA (cfDNA), found circulating in blood plasma, contains a wealth of clinically relevant biological information which can be recovered by minimally-invasive procedures. Next Generation Sequencing (NGS) data obtained from cfDNA, can be used to monitor prenatal health, organ transplant reception or rejection, cancer and other diseases.
ClaretBio’s Clarefy Purification beads are the ultimate choice for retaining short DNA fragments. But we understand labs may have their own purification beads. We’ve put together a handy comparison how to still get the best SRSLY NGS libraries with other, 3rd party beads.