AVAILABLE LITERATURE
We have a wide variety of content that you can download and review
Brochures and Technical Notes
General Product Information
A specialized version of SRSLY that allows combined fragmentomics and methylomics. The workflow is agnostic of the enzymatic methyl conversion kit used.
This data sheet demonstrates the advantages of ClaretBio’s suite of technologies in improving the quality of data captured from clinical samples of poor quality. Here, using DNA and RNA extracted from FFPE tissue that are of low DNA Integrity Number (DIN) or RNA Integrity Number (RIN), we show that the ForShear™>SRSLY® whole genome sequencing workflow and REALLY rNONE™ RNA-Seq workflow generate high quality data even with challenging samples
Learn more about our offering (launch Feb 2025) - a workflow for RNA-Seq from whole blood or blood derived RNA with globin depletion.
APP NOTES
Applications of ClaretBio Technology
This data spotlight demonstrates the compatibility of ClaretBio’s SRSLY library prep with the Element Biosciences’ AVITI™ Systems.
Reduce pipetting steps, gain hands free time! With the Bravo machine, you can prepare SRSLY libraries as easily as you would manually!
Publications
Peer-Reviewed Papers
This paper demonstrates the pitfalls of end-repair in cfDNA fragmentomics and methylation and how SRSLY retains vital cfDNA CpG methylation signals at read termini on 3’ and 5’ ends.
A ligation-based single-stranded library preparation method to analyze cell-free DNA and synthetic oligos
Posters
Conference Posters and Presentations
This poster highlights the effect of end-polishing on cfDNA methylation signal, where especially loss of methylation is seen on the 3’ end. This can be circumvented by using a ssPrep, that does not modify DNA ends.
Use of single-stranded library preparation method in cfDNA fragmentomics
Quarterly newsletter
News and improvements on our kits
Don’t let the “second winter” hold you back—embrace the fresh start of spring! Shake off the rain and explore what’s blooming this quarter at ClaretBio.
Highlight - SRSLY on Nanopore and Aviti Systems
As the days grow longer, ClaretBio starts 2025 off with some exciting new updates! Get ready for upcoming conferences, learn about new products, take note of price adjustments, and catch up on the latest SRSLY cited publications.
As the crisp autumn air rolls in and the leaves begin to turn, it’s time to trade your beach towels for cozy sweaters and dive into a fang-tastic season with Claret Bio. Our Q4 newsletter is packed with spook-tacular updates, treats, and opportunities to help you harvest new insights in your research. Let’s take a stroll through the haunted happenings at Claret this fall!
As the sun shines bright and the days grow longer, it’s time to bask in the warmth of summer. Just like the vibrant energy of the season, our Q3 newsletter is filled with sizzling updates and opportunities to learn what is in Claret’s cooler. Dive into the latest publications and make this summer one-to-remember.