In this webinar series we hope to have insightful discussions on our favorite topics - degraded DNA and how SRSLY may help in capturing fragmentary signals.
In this webinar, Dr. Emmy Wesdorp will present their study on pediatric respiratory disease highlighted in their recent paper. titled NGS-based Aspergillus Detection in Plasma and Lung Lavage of Children with Invasive Pulmonary Aspergillosis. Learn how they worked with a unique sample type to generate next generation sequencing data for detection of Aspergillosis using SRSLY.
Title:
Short-read cfDNA shotgun sequencing for pathogen detection: finding the needle in the haystack
Speaker Bio:
Emmy Wesdorp is a postdoctoral bioinformatician and translational researcher based in the Netherlands, working at the intersection of molecular diagnostics, infectious disease, and pediatric oncology. She is affiliated with the Princess Máxima Center and collaborates with the University Medical Center Utrecht (UMCU), where her research focuses on developing non‑ and minimally invasive liquid biopsy approaches for pediatric oncology and pathogen detection.
Her most recent PhD, conducted at UMCU under the supervision of Prof. Jeroen de Ridder, “Detection of Pathogens through Liquid Biopsy Shotgun Sequencing”, explored how sequencing cell‑free DNA (cfDNA) from blood and other body fluids can identify bacteria and fungi in challenging clinical scenarios, such as immunocompromised children or cases of foal neonatal sepsis. In her work, she applied both standard KAPA and Claret SRSLY library preparations, aiming to detect the extremely sparse microbial signal, the metaphorical “needle in the haystack”.
View previous webinars and presentations here. Revisit this space for upcoming webinars.
INTERESTED IN PRESENTING?
Write to us at info@claretbio.com
View previous webinars and presentations here. Revisit this space for upcoming webinars.
Interested in presenting?
Write to us at info@claretbio.com